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The Ohio State University exerts a significant influence on Columbus. Founded as a land-grant college in 1870, today it is a major research and teaching institution with one of the largest single-campus enrollments in the county. Columbus is a center for education with numerous other colleges and universities. In the city are Franklin University (1902), Capital University (1830), Ohio Dominican College (1911), the Columbus College of Art and Design (1879), and Pontifical College Josephinum (1888). Nearby institutions are Denison University (1831), in Granville; Otterbein College (1847), in Westerville; and Ohio Wesleyan University (1842), in Delaware. The DeVry Institute of Technology was founded in 1952 to provide technical training. The Ohio Academy of Science maintains its offices in Columbus, as does the Ohio Historical Society. The Ohio State School for the Blind and Deaf, founded in 1832, was one of the first such facilities in this country.
Prominent among the cultural institutions in Columbus is the Ohio Historical Center, housing a museum devoted to both Ohio and American history before European contact, and including a nearby open-air museum depicting an Ohio village of the mid-1800s. The Wexner Center for the Arts of The Ohio State University is noted for its daring architecture that is a setting for contemporary visual and performing arts, while the Columbus Museum of Art houses one of the nation's best collections of mid-19th to mid-20th century American paintings. The Center of Science and Industry features hundreds of interactive exhibits on science, industry, and history. Places of particular interest are the Greek Revival Statehouse, completed in 1861 and one of the most distinctive state capitols; Camp Chase Confederate Cemetery; and the Santa Maria, a full-scale replica of the flagship of Christopher Columbus, built to commemorate the 500th anniversary of his voyage. The city also supports a symphony orchestra and opera and ballet companies.