Mayagüez, city, in Mayagüez Municipality, western Puerto Rico, a major seaport on Mona Passage. Its industries include tuna processing, and the manufacture of pharmaceuticals and clothing. In the city are the University of Puerto Rico, Mayagüez Campus (1911), a zoo, several historic buildings, and an agricultural research center with a large collection of tropical plants. The community, founded in 1760 and made a city in 1877, was badly damaged by an earthquake in 1918. Population (1990) 100,371.Microsoft® Encarta® Online Encyclopedia 2001
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